Expertise and Current Research Activity
As a Breast Medical Oncologist I have dedicated my career to the prevention, and treatment of breast cancer and reduction of long term effects of cancer treatment. I am best known for development of the random peri-areolar fine needle aspiration (RPFNA) technique as a comfortable, minimally invasive method of harvesting breast tissue for stratification of risk for development of breast cancer and of great use in early phase prevention trials to help assess response to a new prevention intervention. The majority of my research activities have been devoted to developing effective but well tolerated interventions to prevent breast cancer which will not induce menopause symptoms as do the standard medical treatments for prevention of breast cancer. We have ongoing clinical trials using lignans (anti-inflammatory and mildly anti-estrogenic compounds found in high concentration in flaxseed) in premenopausal women, high dose omega-3 fatty acids ( anti-inflammatory) in pre and postmenopausal women, and aromatase inhibitors in postmenopausal women needing hormone supplementation therapy. I also perform research in cancer survivorship. I am the Program leader for Cancer Prevention at the University of Kansas Cancer Center, Immediate past Chair of the American Society of Clinical Oncology Cancer Prevention Committee, Co- Chair the Survivorship Committee in the Southwest Oncology Research Group and am on several national guideline committees for the Prevention and Treatment of Breast Cancer. I also maintain an active clinical practice focused on the management and treatment of women with breast cancer.